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We engineer complex human models to dissect how cell-to-cell and cross-tissue interactions shape health and disease. By recreating specialised microenvironments – from bone marrow to cardiac tissue – we study how ageing and disease can drive changes in these niches. Our goal is to ultimately use these approaches as translational tools to identify new therapies and validate them in relevant, human pre-clinical platforms.

Our team

Collaborators

  • Prof Anindita Roy – Dept. of Paediatrics
  • Dr Sarah Gooding – MRC WIMM / Oxford Translational Myeloma Centre
  • Dr Bethan Psaila – MRC WIMM & Ludwig Institute
  • Prof Adam Mead – MRC WIMM
  • Prof Sarah Waters – Mathematical Institute
  • Prof Georg Hollander – Institute of Developmental & Regenerative Medicine
  • Dr Julie Rayes – University of Birmingham, Institute of Cardiovascular Sciences
  • Dr Amirpasha Moetazedian – University of Hull, School of Engineering
  • Dr Gowsihan Poologasundarampillai – University of Birmingham, School of Dentistry

Funding Bodies